Azo-Dye Carcinogenesis: Ribonucleotides and Ribonucleases
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چکیده
منابع مشابه
Nitrogen mustard inhibition of azo dye carcinogenesis.
Cellular growth and development may be al tered appreciably by administration of the nitro gen mustards. The chemotherapeutic value of these compounds in the treatment of leukemia and other neoplasms has been well established (5). In addition, the studies reported by Auerbach, Ta turn, Karnofsky, and others have indicated that these agents are mutagenic for Drosophila (1, @), Neurospora (@1), b...
متن کاملInhibition of azo dye carcinogenesis by thorotrast and iron oxide.
Evidence that the reticulo-endothelial system (R.E.S.) may be involved in the carcinogenic proc ess has been presented by Stern and Willheim (22) and by Jaffe (11). This system has also been im plicated in the metabolism of certain fat-soluble materials such as Vitamin A (3,10,17) and choles terol (3, 23) and the water-soluble vitamin, riboflavin (2, 9, 10). Since riboflavin is a factor in the ...
متن کاملRat Liver Parenchymal Cell Function during Azo Dye Carcinogenesis.
(I†• tagged) rose bengal uptake-excre tion test for liver function, as described by Taplin et al. (21), has proven to be a valuable test for a quantitative measure of liver function. In rats, I†• rose bengal uptake and excretion are definitively related to parenchymal cell function (21). Mendeloff (10) showed by fluorescence that injected rose bengal is localized only in parenchymal cells o...
متن کاملStudies in Carcinogenesis with Azo Compounds II. The Action of Azo Compounds in Mice, and the Bearing Thereof on Theories of Azo Dye Carcinogenesis*
The results of earlier investigations of the carcinogenic action of azo dyes in rats were summarized by Kinosita in 1937 and 1940 (22, 23), and by Hartwell in 1941 (17). Since then much work has been done involving various types of controlled, restricted diets and a theory has been evolved (19) to account for the activity of certain dyes and the inactivity of others. A short review of this work...
متن کاملStudies in carcinogenesis with azo compounds; the action of azo compounds in mice, and the bearing thereof on theories of azo dye carcinogenesis.
The results of earlier investigations of the carcinogenic action of azo dyes in rats were summarized by Kinosita in 1937 and 1940 (22, 23), and by Hartwell in 1941 (17). Since then much work has been done involving various types of controlled, restricted diets and a theory has been evolved (19) to account for the activity of certain dyes and the inactivity of others. A short review of this work...
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ژورنال
عنوان ژورنال: British Journal of Cancer
سال: 1963
ISSN: 0007-0920,1532-1827
DOI: 10.1038/bjc.1963.96